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This prolonged gastric retention can increase intragastric pressure and potentially promote the reflux of stomach contents into the oesophagus, leading to symptoms of heartburn, regurgitation, and discomfort

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That is clinically relevant wound-healing evidence, but it involved a specific topical wound-care protocol and should not be generalized to unsupervised use

Without patent protection, no pharmaceutical company can recoup the $100M+ cost of running the clinical trials required for FDA approval