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Skin, being the largest organ of the human body, is composed of three main layers: Epidermis : Sublayers include stratum corneum, stratum lucidum, stratum granulosum, stratum spinosum, and stratum basale

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In way to optimize the conduct of experiments and increase their acceptability in compliance with regulations in animal experimentation focusing on one of the 3Rs, the refinement 36,37 , we used APAP as a new therapeutic refinement tool to relieve the mice in an infectious model of toxoplasmosis

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Common side effects may include local irritation or discomfort, while systemic side effects could include allergic reactions