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Likewise, during activity the mean decrease in pain score was 11.69 mm/h (95%CI 10.10-13.28 mm/h) for indomethacin and 11.38 mm/h (95%CI 9.98-12.79 mm/h) for prednisolone
26 Only two of the reviewed studies were RCTs of B12 on its own in children with ASD, both using subcutaneous methyl-B12
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Injections may be considered when there is a risk of rapid deterioration, significant neurological or haematological concern, or problems taking oral treatment reliably
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