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Yet history tells us: some patients and vendors will try anyway

Over-interpretation of secondary outcomes may lead to spurious inferences, underscoring the need for caution when translating these findings into clinical reassurance.This aligns with emerging data linking metabolic improvements such as weight loss, insulin sensitivity, and reduced inflammation to decreased malignancy risk in high-risk populations with type 2 diabetes or obesity (Marso et al., 2016a

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The agents promote insulin secretion by the pancreatic islet cells and inhibit gluconeogenesis by the liver

Weight fluctuates with hydration, hormones, and muscle changes