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(Pt 2) Acosta IC, Alonzo F
You do not need dramatic weight loss as an outcome
Supports nutrient intake during reduced-appetite phases
However, this reduction in nutritional intake may lead to: Dehydration Reduced fluid consumption alongside decreased food intake Hypoglycaemia Lower blood glucose levels, particularly in patients taking concurrent glucose-lowering medications such as insulin or sulfonylureas Potential electrolyte changes Particularly if experiencing gastrointestinal side effects Caffeine withdrawal Unintentional reduction in habitual caffeine consumption The medication's gastrointestinal effects, including nausea and vomiting (very common adverse reactions), may indirectly contribute to headaches through dehydration
As a once-daily oral pill, orforglipron might be an attractive option for patients that choose orlistat over GLP-1 jabs
