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Thats a dopamine loop

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I wanted to share a relevant article for this topic based on a social media listening study, which found slightly enhanced/extended effects, with a delayed onset, of MDMA, arguably due to the GLP1-RA-associated delayed gastric emptying

For instance, microdosing, which involves administering smaller doses, has been shown to promote significant weight loss with enhanced tolerability

These include certain antipsychotics (olanzapine, clozapine), mood stabilizers (valproate, lithium), antidepressants (mirtazapine, paroxetine), corticosteroids, and some diabetes medications like insulin or sulfonylureas