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DPP-4 inhibitors may be preferred for: Patients unable or unwilling to use injectable therapies Elderly individuals where the lower hypoglycaemia risk is particularly valuable Those at high risk of hypoglycaemia from other medications Patients requiring modest glycaemic improvements Individuals where weight neutrality is acceptable or desired Important cautions and contraindications: Do not combine a GLP-1 receptor agonist with a DPP-4 inhibitor
Peters SAE, Huxley RR, Woodward M (2014) Diabetes as a risk factor for stroke in women compared with men: a systematic review and meta-analysis of 64 cohorts, including 775,385 individuals and 12,539 strokes
Storage above 8C for 48 hours degrades 3040% of active compound even if the vial appears unchanged
Additional monitoring considerations include assessing for symptoms of pancreatitis (severe, persistent abdominal pain), gallbladder disease (right upper quadrant pain, fever), or diabetic retinopathy changes
Riboflavin: Riboflavin, also known as Vitamin B2, plays a crucial role in converting carbs, proteins, and fats into energy
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