Emerging tools for dissecting drug resistance Single-cell omics Single-cell omics technologies enable high-throughput profiling of the genome, transcriptome, epigenome, proteome, and metabolome at the individual cell level
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Considerations are based on IGF-1 biology, including its influence on growth factor signaling and metabolic regulation
Nevertheless, by using a functional bioluminescence resonance energy transfer (BRET) technique, we could not find significant differences in the ability of the D 4.2 R, D 4.4 R or D 4.7 R polymorphic variants to promote dopamine-induced activation of any of the five Gi/o protein subtypes (35)
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