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They focused on dorsolateral PFC activity and found no association with changes in ghrelin levels (Sewaybricker et al., 2021)

Obesity Treatment Is Expanding Beyond Medication According to the authors, GLP-1 receptor agonists have significantly changed the obesity treatment landscape

Phase 2 and Phase 3 trials so far havent reported an excess of serious heart events on retatrutide, but they were short and werent designed to test that question