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References: (1) P B Johansen, J Nowak, C Skjrbk, et al (1999) Ipamorelin, a new growth-hormone-releasing peptide, induces longitudinal bone growth in rats Growth Hormone & IGF Research, Volume 9, Issue 2, May 1999, Pages 106-113

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Assuming that the lower temperature (20 C) enhanced glutathione biosynthesis in batch fermentation and hindered cell growth in the fed-batch system, the culture temperature was increased to 30 Cthe optimal growth temperature for S

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