3 What is GLP-1 and why it matters GLP-1 is an incretin hormone that is primarily secreted by enteroendocrine L-cells in the distal small intestine and colon in response to nutrient ingestion, including carbohydrates, fats, and proteins
Add extra water around dose days, since early nausea may reduce fluid intake
The inactivation of GPX4 in the proximal tubules could cause ferroptosis and further induce AKI (Yang et al., 2014)
Earlier this year, Hims & Hers said it was launching a compounded version of Novo Nordisk's newly approved Wegovy pill, a major new product in its weight-loss franchise, only to backtrack after a lawsuit from the pharma company and a pledge from the FDA to restrict compounding of GLP-1 agonist medicines that are being "mass-marketed"
On April 24, a federal judge rejected a bid by compounding pharmacies to continue selling the less expensive versions