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J Biol Chem 2003

Increase fiber intake gradually to support regularity Aim for 64 to 80 ounces of water daily Magnesium supplements can help with constipation Probiotics may improve overall digestive comfort Light walking after meals aids digestion Avoid artificial sweeteners which can worsen GI symptoms Fatigue is reported by some women, particularly during dose escalation

The mean weight loss reached 28.3% at 80 weeks and 30.3% at 104 weeks in the higher-BMI cohort [1]

These results underscore the need for future studies with larger sample sizes, and measurements of potential confounders, especially weight and biomarkers (i.e., HbA1c) to confirm our findings

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