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FGF21 also inhibits fibrogenesis in two mouse models of chemically-induced liver injury, dimethylnitrosamine- (217) or thioacetamide-induced fibrogenesis (220), by blocking TGF- expression and signaling, and NF-B activation
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The FTC's Health Products Compliance Guidance requires that weight-loss claims be backed by "competent and reliable scientific evidence," which generally means at least one well-designed human trial on the specific finished product
It is present in every cell but is most concentrated in the liver, the bodys main biochemical synthesizer, and detoxification organ
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