People with a history of allergy to cobalamin should avoid taking vitamin B12
As a supplement, chanca piedra is reported to help with a variety of conditions related to the digestive system, liver, and kidneys
The mechanistic consequence is that GHRP-6 activates the full biological program that ghrelin controls not just GH secretion, but somatostatin suppression, appetite signaling via NPY/AgRP pathways, gastric motility, and elements of the reward circuitry
"I have replaced the serotonin [and dopamine] and happiness I would get from eating all those foods with hobbies in my real life" such as weightlifting, knitting, playing video games and, most recently, running
The GIP component accounts for much of that additional efficacy