88 Stability and permeability are major concerns for peptides
Resources We Trust Mayo Clinic Health System: Weigh Benefits, Risks Carefully Before Taking Off-Label Medication Johns Hopkins School of Public Health: Overweight and Obesity in People With Type 1 Diabetes Nearly Same as General Population Yale Medicine: Why Your Cardiologist May Prescribe Semaglutide (Wegovy) T1D Exchange: Using GLP-1 Medications in Type 1 Diabetes The Harvard Gazette: Losing Fat Is Good, But Losing Muscle Isnt Fang M et al
Researchers note that intranasal delivery may especially increase the bioavailability of peptide therapeutics and present an appealing alternative to injection [14, 15, 16]
The available clinical material was small, old, brief, incompletely reported, and not sufficient to establish a dependable benefit-risk conclusion
Following overnight selection, plasmids were collected from 35 ml of culture by midiprep following the manufacturers protocols and prepped for high-throughput amplicon sequencing