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This enabled us to assess whether the structural differences and conformational dynamics observed in the Cagri and rAmy bound AMYR structures alter the nature of Gs protein interaction (Supplementary Fig
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Recent findings have shown that OA synovial exosomes carrying miR-19b-3p enhance ferroptosis in chondrocytes by targeting SLC7A1 (57), highlighting the pathological crosstalk between synovium and cartilage
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