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The FDA has received reports of patients erroneously injecting too much or healthcare providers calculating incorrect doses resulting in the need for medical attention or hospitalization

Cancer Res 59 : 35883591 Zhang L, Kashanchi F, Zhan Q, Zhan S, Brady JN, Fornace AJ, Seth P, Helman LJ (1996) Regulation of insulin-like growth factor II P3 promotor by p53: a potential mechanism for tumorigenesis