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Results Inducible deletion of Keap1 in adult MuSCs impairs their regenerative functions in vivo The transition of adult MuSCs from quiescence to proliferation involves greatly increased RNA and protein production, mitochondria biogenesis and metabolic reprogramming, which results in an elevation of intracellular ROS levels 20,21,22,23,24,25

doi: 10.1016/j.ebr.2021.100452 39 LobKBassell-HawkinsJPatilRNieDBartoliniL

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Population estimates for the UK, England, Wales, Scotland, and Northern Ireland: mid-2022

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