Creatine monohydrate (35 g daily) is the most evidence-backed supplement for muscle preservation during caloric deficit
Options include: Metoclopramide : May help with delayed gastric emptying but should only be used for short courses (maximum 5 days) due to risk of neurological side effects Prochlorperazine : Can be effective for nausea and vomiting Cyclizine : An alternative that works through a different mechanism Ondansetron : Sometimes used but may cause constipation Domperidone : Used cautiously due to risk of heart rhythm problems (QT prolongation), particularly in older adults, those with heart conditions, or those taking other medications affecting heart rhythm For people with diabetes, it's important to follow sick-day rules if experiencing vomiting
In a twist, the study found that although there was a small increase in diabetic retinopathy, GLP-1 use appeared to protect against the conditions progression and sight-threatening complications
Darios F, Corti O, Lcking CB, Hampe C, Muriel MP, Abbas N, Gu WJ, Hirsch EC, Rooney T, Ruberg M, Brice A
EGCG acts as a strong antioxidant, being 100 times stronger than vitamin C and 25 times stronger than E