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Senolytic FOXO4-DRI can inhibit FOXO4 binding by disrupting the p53-FOXO4 interaction and selectively cause apoptosis via p53 nuclear exclusion in senescent cells and aging mouse models, which may be a promising approach for preventing senescence 11

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

hNF-1 was grown and maintained as monolayer cultures at 37 C in 5% CO 2 in a humidified atmosphere, using DMEM (low glucose with l-glutamine and phenol red, Sigma-Aldrich Co., Llc.) and 5 vol% FBS (Thermo Fisher Scientific Inc.)

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For long-term storage of lyophilized research materials, refrigeration or freezing is commonly used in laboratory settings