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As estrogen levels drop with fat loss, vaginal tissues can become thinner and less lubricated, which may cause dryness or pain during sex
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Safety Considerations When Combining These Medications The combination of metformin and GLP-1 receptor agonists is generally considered safe , with extensive clinical trial data supporting their concurrent use
This suggests the presence of compensatory mechanisms involving other hypothalamic or extra-hypothalamic regions [80,93]
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