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Healthcare professionals should discuss this risk as part of informed consent when initiating treatment

Despite acknowledging that the "highly effective" injections had "transformed the treatment of obesity," the BMJ Group's release noted that "it is estimated that around half of people with obesity discontinue GLP-1 drugs within 12 months, so its important to understand what happens to body weight and risk markers for conditions like diabetes and heart disease after stopping treatment." The release stated, "To do this, a team of researchers from the University of Oxford searched registries and databases for trials and observational studies that compared the effects of any medication licensed for weight loss in adults with any non-drug weight loss intervention (behavioural weight management programmes) or placebo." Researchers looked at 37 studies published up to February 2025 involving 9,341 participants, per the data, which pointed out that the average duration of weight loss treatment was 39 weeks, with an average follow-up of 32 weeks

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GH-RH analogs New approaches to the treatment of BPH using analogs of GH-RH In this article, we first reviewed the action and uses of agonists and antagonists of LH-RH, and we will now review the development of agonists and antagonists of GH-RH before focusing on their application as single or combined agents for the treatment of BPH