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Excess accumulation of Cr negatively influences the activity of the cell cycle and causes an imbalance of elemental concentration, enzyme activity, and other metabolic processes, which leads to the induced generation of reactive oxygen species and oxidative stress in several plant species [36]
As detected by DCFH-DA and C11-BODIPY staining of frozen sections of the PDX tumors, the ROS levels and lipid peroxidation levels of the PDX tumors with high ACTL6A expression were lower, and they were significantly increased by BSO treatment
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