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When your body suddenly consumes fewer calories, it may temporarily feel tired while adjusting

Your clinician will discuss with you which dose should be your maintenance dose

Kynurenine is predominantly metabolized to the N -methyl-d-aspartate (NMDA) receptor agonist quinolinic acid (QUIN) in the inflammatory state, contributing to the accumulation of glutamate in the extracellular space, leading to changes in network connectivity associated with depression, fatigue and cognitive impairment

Think of this as a two-key system rather than a single lock and key

Research design and methods: We conducted a retrospective cohort study of 5,384 adults with T2D, enrolled in Leumit Health Services, who initiated semaglutide therapy between February 1, 2019, and December 31, 2022