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Specifically, thiamine is important for glucose metabolism [51] and type 2 diabetics have been observed to have lower-than-average thiamine levels, suggesting that some degree of thiamine deficiency may play a role in the onset of diabetes
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In response to eating, increased levels of GLP-1 stimulate insulin secretion and inhibit glucagon release leading to lower blood glucose levels
(Wikipedia) In senescent cells (cells that have permanently exited the cellcycle, accumulate damage, and secrete inflammatory factors), FOXO4 expression goes up and helps bind p53 in the nucleus, preventing p53 from driving those cells into apoptosis
ZhangZLiuYFengWMaoPYangJZhaoZet al
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