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Decorin upregulation represents a fourth mechanism: decorin is a proteoglycan that organizes collagen fibril assembly and suppresses TGF-beta-mediated fibrosis, so its upregulation by GHK-Cu may support organized tissue repair with reduced scar formation
Unlike an acute sports injury, osteoarthritis develops gradually as cartilage deteriorates and changes occur throughout the joint, including the surrounding bone, ligaments, and synovial tissue
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gammadelta T cells in tissue physiology and surveillance
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