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The most responsible position sits between those two extremes
Researchers should define the main question before selecting a model: whether the study is testing cytoprotection, migration, proliferation-associated endpoints, angiogenesis, extracellular matrix remodeling, endothelial signaling, or tissue-level recovery
Presented for research literature review only Khan NA et al
Almroth, B
With respect to skeletal repair, it has been examined in models of bone injury and structural defects
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