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While muscle cramps are not listed as a common side effect in FDA labeling, some patients report experiencing them during treatment
Arterburn DE, Johnson E, Coleman KJ, Herrinton LJ, Courcoulas AP, Fisher D, et al
Leptin, produced by fat cells, reduces hunger and signals to the brain when youre full and have enough energy stored
The reduction of inflammatory signaling may play an additional role in the analgesic effects of GLP-1R agonists against neuropathic pain [32, 34, 35]
In the STEP 1 trial, adults without diabetes who received semaglutide lost an average of 14.9% of their starting body weight over 68 weeks, compared to 2.4% in the placebo group
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