In addition to alcohol-related gastrointestinal chronic conditions like peptic ulcer disease and esophagitis, acute alcohol intoxication may lead to acute esophagitis and gastritis with severe nausea and vomiting and in some cases life-threating complications due to e.g., bleeding and Mallory-Weiss syndrome (tear or laceration of the gastroesophageal junction) [42]
At the same time, researchers noted that GLP-1 drugs may benefit some eye conditions, including age related macular degeneration and uveitis
Breath alcohol was measured every 30 minutes, blood glucose was measured twice, and three hours after the session participants again answered subjective questions
For retatrutide, the safety database is smaller because the compound is still in Phase 3 trials
The international trial register clinicaltrials.gov was searched for published and unpublished studies by searching each of the individual drugs combined with the terms pregnancy, diabetes mellitus, reproduction and lactation