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BAs are essential endocrine molecules that control metabolic homeostasis via nuclear and membrane-bound receptors, Farnesoid X receptor (FXR) and Takeda G protein-coupled receptor 5 (TGR5), respectively
In addition, companies are engaged in developing novel GLP-1 products
Systematic review and meta-analysis for prevention of cardiovascular complications using GLP-1 receptor agonists and SGLT-2 inhibitors in obese diabetic patients
www.calrapp.org) and visualized using GraphPad Prism
11, 19, 20 It is important to find a consensus in understanding the molecular mechanisms of the postulated pathologies and to know to which extent the animal data can be extrapolated
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