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Note: animal studies indicate that high doses of DPP-4 inhibitors & GLP-1 agonists cause expansion of cells of the pancreatic ductal glands and can cause premalignant pancreatic intraepithelial lesions (PanIN) that have the potential to progress to pancreatic adenocarcinoma
Richardsen noted this was the fifth first-to-market entry of a Teva generic this year. Liraglutide injection is indicated for patients age 12 and older diagnosed with obesity
Look for unsweetened varieties with live cultures for added gut benefits
According to the company's blog content, users should expect a gradual titration process that involves starting at lower doses and increasing over weeks or months
The drugs, which can cost more than US$1,000 (S$1,287) a month for US residents, could offer starting oral doses for as little as US$150 under the deal, though the price for injectables would be higher
