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LCMS/MS analysis was performed using an Advance nanoLC (BrukerMichrom, Auburn, CA, USA) and LTQ linear ion trap mass spectrometer (Thermo Fisher Scientific) equipped with a NANOHPLC capillary column C18 (0.075 mm ID 150 mm length, 3 m particle size, Nikkyo Technos, Tokyo, Japan) using a linear gradient (25 min, 535% CH 3 CN /0.1% formic acid) at a flow rate of 300 nL/min

1 mg to 2 mg) First-line OTC: Bismuth subsalicylate 262-524 mg before meals Second-line OTC: Simethicone 125-250 mg after meals

El proceso de preparacin puede variar segn el tipo de dieta y la forma de administracin, pero pueden seguirse algunas pautas generales

Additional References FDAs Concerns with Unapproved GLP-1 Drugs Used for Weight Loss - U.S

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