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However, combining tirzepatide with peptides targeting different pathways, such as BPC-157 for gut health or growth hormone secretagogues for body composition, is more common

While improvements in diet and physical activity might explain some of the overall improvement, they do not account for the differences observed between the active and placebo groups

Patients with active suicidal ideation, recent psychiatric hospitalization, or unstable bipolar disorder should not start a GLP-1 agent through any telehealth platform without documented coordination with their treating psychiatrist

Starting Dose Recommendations Most protocols begin at 0.5 mg to 1 mg once weekly