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Nature 486 , 222227 (2012)
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Manufacturers must carefully balance regulatory risk with commercial opportunity, making strategic planning essential for sustainable market participation
Discussing alternative therapies or having regular nutrient IV therapy and/or vitamin B12 injections can help
Methods: To study Aster function in the liver, we generated mice with hepatocyte-specific deletion of either Aster-A (L-A knockout (KO)), Aster-C (L-C KO) or both (L-A/C KO) and conducted lipidomic analysis with in vivo tracer studies with [14C]cholesterol
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