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GSH is exclusively degraded at the extracellular level by cells expressing -glutamyltranspeptidase (GGT), such as those of the hepatobiliary tree and of other organs like the heart, kidney, lungs, pancreas, and seminal vesicles
Clearance Total body clearance was found to be a mean of 4L/h
Alcohol use, for example, so taxes Glutathione in the liver that depleted levels are seen in the lungs as well
Very short half-life
Ceriello A
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