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Those switched to placebo regained approximately half their lost weight within 52 weeks
9 Rather than functioning as a stand-alone approach, glutathione is more commonly considered as one variable within complex mood and inflammatory profiles, especially when oxidative stress or low-grade inflammation appears to contribute to the overall clinical picture
Also, the variability in follow-up duration across the included RCTs can affect event capture rates and risk estimates, as shorter trials may underreport long-term outcomes while longer trials may reflect cumulative risks
~25-29% total reduction possible by 68 weeks for those who stay consistent
This observation leads to the question of whether supraphysiological stimulation (as occurs with GLP-1RA use) could accelerate the progression of PanIN lesions into PDAC
