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3.1.4 Nrf2/Slc7a11/GPX4 axis and myocardial injury In ischemia-reperfusion injury (IRI), a well-established model for myocardial injury, ozone pre-treatment mitigates myocardial ferroptosis by activating the Nrf2/solute carrier family 7 member 11 (Slc7a11)/GPX4 axis
Preclinical protocols vary widely in dose, species, and tissue target
It inhibits growth but does not sterilize
5 State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China
Mitochondrial biogenesis and dynamics in the developing and diseased heart
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