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Population prevalence and estimated birth incidence and mortality rate for people with Prader-Willi syndrome in one UK health region

These symptoms are usually mild and subside after a short period

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Long-term human safety data does not exist, which is the main caution

In June 2025, the European Medicines Agency officially recognized NAION as a very rare side effect of semaglutide after reviewing all data, concluding it may affect up to 1 in 10,000 people and recommending product information updates