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Especially with CLA frequently being marketed as a weight loss supplement, this could create a dangerous counterintuitive effect on those trying to lose weight

Pharmacokinetics (Coskun et al., Cell Metabolism 2022) Phase 1 PK data established the ~6-day half-life and once-weekly dosing rationale

She notes that certain centers of the brain that are involved in the reward processing centers light up when people who are sleep-restricted see these foods. The relationship between sleep, hormones and weight Sleep (or lack thereof) also impacts your bodys appetite regulation hormones

Shmerling (2024)

Nausea, reduced appetite for nutritious foods, or constipation can make it harder to eat enough protein, which may slightly slow early weight loss