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In the STEP-4 randomized trial (Rubino and colleagues, JAMA, 2021), the 803 adults who switched to placebo at week 20 regained about 6.9 percent of body weight over the next 48 weeks, while those who continued semaglutide kept losing
The semaglutide component matters less than the baseline deficiency risk
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**Daily Value not established
Depress the plunger slowly, letting the water run down the inside wall of the vial and onto the powder gently
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