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benefit: FDA only looked at risk, ignored benefits Off-label use: Doctors prescribe drugs off-label all the time Patient access: People are suffering and need options Regulatory capture: Big Pharma doesn't want cheap peptides competing The problem with these arguments: It's NOT off-label use Off-label only applies to FDA-approved drugs
It may favor those with persistent pain or inflammation due to physical exertions
In some cases, its used before or after surgery to support the healing process
This combination strategy is also highlighted in Novo Nordisk communications about regulatory filings, describing cagrilintide as the amylin analogue component paired with semaglutide
Further studies with longer follow-up are needed to compare cardiovascular outcomes
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