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When deficiency is suspected based on clinical features (fatigue, paraesthesia, cognitive changes) or risk factors (vegan diet, gastric surgery, certain medications), serum B12 measurement guides appropriate intervention
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Deletion of monoglyceride lipase in astrocytes attenuates lipopolysaccharide-induced neuroinflammation
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Individuals with malabsorption conditions, severe deficiency, or those who havent responded to oral supplements typically benefit most from injections
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