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Studies published in Diabetes Care and Obesity show that dose escalation during plateaus produces additional 37% body weight loss in 6070% of patients

Alterations in DNA damage repair (DDR) Molecular mechanisms in DDR DDR safeguards genomic stability under genotoxic stress, and its deficiency confers pronounced sensitivity to genotoxic therapies and PARP inhibitors while also driving resistance through repair restoration or pathway bypass

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This dual-action approach has demonstrated even greater results, with some patients losing over 20% of their body weight