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Pyrimethamine continues to be used, particularly in sub-Saharan Africa, for intermittent preventive treatment during pregnancy, where it helps reduce the risk of low birth weight associated with malaria [810], but also for seasonal malaria chemoprevention among children [11]
A much lower rate of infection was noted in the treatment group compared to placebo as well
Medication delivered directly through an IV is typically more effective than medication delivered through an oral route
L.Casado-DazA.et al (2020)
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