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[2] Andreasen CR, Andersen A, Knop FK, et al
Reduced glutathione is the active, antioxidant form that provides therapeutic benefits
Mechanistic insights from the REMODEL trial further support its role, identifying improvements in renal microvascular function through reduction of kidney fat, improved glomerular hemodynamics, attenuation of endothelial injury via metabolic reprogramming, and decreased inflammation and fibrosis
Independent studies have reported increased oxidative stress and altered ETC activity (120) and decreased levels of antioxidants and antioxidant enzymes (121) in the brain tissue of patients with depression
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