The reason why [semaglutide] works is not just the fact that it depresses appetite, its that it gets insulin to work better
JCI Insight 8 , e170419 (2023)

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In a study, research found that it reduced inflammation, decreased antibody numbers and prevented heart problems (x)
The studys limitations include the cross-sectional nature, which precludes establishing causality, self-reporting of anthropometric and demographic data, which might lead to bias, and unidentified confounding