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GSH + amino acid -Glu-amino acid +CysH-Gly (amino group transfer) GSH + H2O Glu +CysH-Gly (hydrolysis) GSH + GSH -Glu-GSH +CysH-Gly (amino group transfer) 3
In detail, BM stimulated by -glucan induces expansion of CD41-biased HSCs and BM subpopulations, followed by enhanced metabolic pathways such as glycolysis, cholesterol synthesis, and mevalonate in HSPCs (251)
Our work highlights B cell-specific alterations that offer novel insights for the understanding of the role of GSH in the regulation of B cells function and defects during disease, such as those caused by viral infections
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