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Researchers interested in this direction can see more details on the efficacy of GLP-1R/GCGR agonists in the treatment of obesity in Sanchez-Garridos review (131)

In summary, our study showed no clear association of serum IGF-1 concentration with ALS risk but with the prognosis of ALS, suggesting that higher IGF-1 concentration could increase survival

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By acting on GLP-1 receptors in the pancreas, it stimulates insulin release and reduces glucagon secretion, resulting in better blood sugar control

Have a severe gastrointestinal disease, such as gastroparesis (delayed stomach emptying)