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In addition to regulating cardiomyocyte function, GLP-1RAs also improve the function of cardiac fibroblasts
This is counterintuitive but well-documented in bariatric medicine literature (Prado et al., Obesity Reviews , 2018)
doi: 10.1056/NEJMoa2301972 14 GarveyWTBlherMOsorto ContrerasCKDaviesMJWinning LehmannEPietilinenKHet al
Since semaglutide is often prescribed for weight loss, people who start taking it may already have a higher risk of lower back pain due to their weight
For example, ritonavir acts as an inhibitor of CYP3A4/5 (ref
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