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Some of the biggest risk factors for B12 deficiency are vegetarian/vegan diets, pregnancy/breastfeeding, and aging

Gender Differences in Alcohol Metabolism Women generally have a lower body water content and higher body fat percentages than men

Form of Vitamin B12: The type of vitamin B12 used also plays a role

[22] [18] Pseudovitamin B 12 is the majority corrinoid in spirulina, an algal dietary supplement sometimes erroneously claimed as having this vitamin activity

Studies published in Biochemical Pharmacology show that NNMT expression increases significantly with aging in skeletal muscle tissue and correlates with impaired muscle stem cell function and reduced regenerative capacity